Paul Offit, MD, director of the Vaccine Education Center at the Children’s Hospital of Philadelphia (CHOP), is more blunt. We developed a vaccine for a good reason.” “We haven’t had much measles and people forget what a bad disease it is-lots of complications, hospitalizations, long-term neurologic deficits. “Maybe the publicity surrounding these Disneyland outbreaks will do some good,” says Diane Griffin, MD, PhD, professor of Molecular Microbiology and Immunology. ![]() According to CDC figures, more than 80 percent of those stricken with measles by the midpoint of last year’s epidemic had avoided vaccination by using nonmedical exemptions. Children with medical contraindications are granted exemptions in all states, and 48 states also allow exemptions on religious and/or personal beliefs. The CDC maintains a recommended vaccination schedule for children, and all states mandate vaccinations before attending school (though the particulars vary). Rates of at least 95 percent, if not higher, are required to readily prevent the disease’s spread and provide “herd immunity.” Analysis has found that in some areas experiencing outbreaks, measles vaccination rates had fallen to as low as 50 percent. Some parents-propelled by misinformation-have come to fear vaccines more than the diseases they prevent. Why the resurgence here of this scourge marked by high fever and rash? Blame declining measles vaccination rates, at least in pockets of the country. Knowledge, Attitudes and Beliefs of School Nurses/Personnel and Associations with Non-Medical Immunization Exemptions. ![]() Salmon DA, Moulton LH, Omer SB, Chace LM, Klassen A, Talebian P, Halsey N. Enhancing Public Confidence in Vaccines through Independent Oversight of Post-Licensure Vaccine Safety. ![]() Baltimore Sun December 2004 Reprinted in the Houston Chronicle. Archives of Pediatrics and Adolescent Medicine. Factors Associated with Refusal of Childhood Vaccines Among Parents of School-Aged Children: A Case-Control Study. Salmon DA, Moulton LH, Omer SB, deHart MP, Stokley S, Halsey NA. Cancer Epidemiology, Biomarkers and Prevention 2005 (Accepted on Dec 2)Ģ. Markers Of Past Infection With Simian Virus 40 And Risk Of Incident Non-Hodgkin Lymphoma In A Maryland Cohort. Rollison DE, Helzlsouer KJ, Halsey NH, Shah KV, Viscidi RP. On-going studies include: persistent poliovirus excretion in immunodeficient children, evaluation of Lyme disease vaccine in children, evaluation of alternative injection devices, and the safety of preservatives and adjuvants in vaccines.ġ. My interest in vaccine safety stems from experience with vaccine-associated paralytic poliomyelitis, increased mortality after high-titer measles vaccines, and differences in response to acellular and wholecell pertussis vaccines. ![]() The control of measles has been a particular focus of interest and I support the ongoing measles and poliomyelitis eradication efforts. I have conducted or participated in epidemiological studies of vaccine-preventable diseases and phase I, II, and III vaccine trials of hepatitis B, hepatitis A, inactivated polio virus, pertussis, Haemophilus influenzae type B, tetanus, Lyme disease, rotavirus, Argentina Hemorrhagic Fever, and influenzae vaccine viruses. My primary research and teaching effort is directed toward the prevention of infectious diseases with the safest vaccines possible.
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